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William M. Southerland

TitleProfessor
Faculty RankProfessor
InstitutionHoward University
DepartmentBiochemistry & Molecular Biology
Address520 W Street NW
.Department of Biochemistry & Molecular Biology
Washington DC 20059
Phone2028069711
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ngwa JS, Nwulia E, Ntekim O, Bedada FB, Kwabi-Addo B, Nadarajah S, Johnson S, Southerland WM, Kwagyan J, Obisesan TO. Aerobic Exercise Training-Induced Changes on DNA Methylation in Mild Cognitively Impaired Elderly African Americans: Gene, Exercise, and Memory Study - GEMS-I. Front Mol Neurosci. 2021; 14:752403. PMID: 35110995.
      Citations:    
    2. Hedges JR, Soliman KFA, Southerland WM, D'Amour G, Fern?ndez-Repollet E, Khan SA, Kumar D, Shikuma CM, Rivers BM, Yates CC, Yanagihara R, Thompson WE, Bond VC, Harris-Hooker S, McClure SA, Ofili EO. Strengthening and Sustaining Inter-Institutional Research Collaborations and Partnerships. Int J Environ Res Public Health. 2021 03 08; 18(5). PMID: 33800316.
      Citations: 3     Fields:    Translation:Humans
    3. Apprey V, Wang S, Tang W, Kittles RA, Southerland WM, Ittmann M, Kwabi-Addo B. Association of Genetic Ancestry With DNA Methylation Changes in Prostate Cancer Disparity. Anticancer Res. 2019 Nov; 39(11):5861-5866. PMID: 31704810.
      Citations: 7     Fields:    Translation:HumansCells
    4. Southerland WM, Swamidass SJ, Payne PRO, Wiley L, Williams-DeVane C. The diversity and disparity in biomedical informatics (DDBI) workshop. Pac Symp Biocomput. 2018; 23:614-617. PMID: 29218919.
      Citations: 1     Fields:    Translation:Humans
    5. Mao L, Fang Y, Campbell M, Southerland WM. Population differentiation in allele frequencies of obesity-associated SNPs. BMC Genomics. 2017 Nov 10; 18(1):861. PMID: 29126384.
      Citations: 17     Fields:    Translation:Humans
    6. Morris KF, Billiot EJ, Billiot FH, Ingle JA, Zack SR, Krauss KB, Lipkowitz KB, Southerland WM, Fang Y. Investigation of Chiral Recognition by Molecular Micelles with Molecular Dynamics Simulations. J Dispers Sci Technol. 2018; 39(1):45-54. PMID: 30294058.
      Citations:    
    7. Ogindo CO, Khraiwesh MH, George M, Brandy Y, Brandy N, Gugssa A, Ashraf M, Abbas M, Southerland WM, Lee CM, Bakare O, Fang Y. Novel drug design for Chagas disease via targeting Trypanosoma cruzi tubulin: Homology modeling and binding pocket prediction on Trypanosoma cruzi tubulin polymerization inhibition by naphthoquinone derivatives. Bioorg Med Chem. 2016 08 15; 24(16):3849-55. PMID: 27345756.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    8. Morris KF, Billiot EJ, Billiot FH, Hoffman CB, Gladis AA, Lipkowitz KB, Southerland WM, Fang Y. Molecular Dynamics Simulation and NMR Investigation of the Association of the ?-Blockers Atenolol and Propranolol with a Chiral Molecular Micelle. Chem Phys. 2015 Aug 18; 457:133-146. PMID: 26257464.
      Citations:    
    9. Morris KF, Billiot EJ, Billiot FH, Gladis AA, Lipkowitz KB, Southerland WM, Fang Y. A Molecular Dynamics Simulation Study of the Association of 1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate Enantiomers with a Chiral Molecular Micelle. Chem Phys. 2014 Aug 17; 439:36-43. PMID: 25083022.
      Citations:    
    10. Morris KF, Billiot EJ, Billiot FH, Lipkowitz KB, Southerland WM, Fang Y. A Molecular Dynamics Simulation Study of Two Dipeptide Based Molecular Micelles: Effect of Amino Acid Order. Open J Phys Chem. 2013 Feb 01; 3(1):20-29. PMID: 23951550.
      Citations:    
    11. Morris KF, Billiot EJ, Billiot FH, Lipkowitz KB, Southerland WM, Fang Y. Investigation of Chiral Molecular Micelles by NMR Spectroscopy and Molecular Dynamics Simulation. Open J Phys Chem. 2012 Nov 01; 2(4):240-251. PMID: 23991355.
      Citations:    
    12. Li H, Liu C, Burge L, Southerland W. Identification of two post-translational modifications via tandem mass spectrometry. Int J Comput Biol Drug Des. 2012; 5(3-4):314-24. PMID: 23013656.
      Citations:    Fields:    Translation:HumansCells
    13. Zhao Y, Hao Y, Ji H, Fang Y, Guo Y, Sha W, Zhou Y, Pang X, Southerland WM, Califano JA, Gu X. Combination effects of salvianolic acid B with low-dose celecoxib on inhibition of head and neck squamous cell carcinoma growth in vitro and in vivo. Cancer Prev Res (Phila). 2010 Jun; 3(6):787-96. PMID: 20501859.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    14. Hu JZ, Bai L, Chen DG, Xu QT, Southerland WM. Computational investigation of the anti-HIV activity of Chinese medicinal formula Three-Huang Powder. Interdiscip Sci. 2010 Jun; 2(2):151-6. PMID: 20640783.
      Citations: 5     Fields:    Translation:HumansCells
    15. Chen P, Liu C, Burge L, Li J, Mohammad M, Southerland W, Gloster C, Wang B. DomSVR: domain boundary prediction with support vector regression from sequence information alone. Amino Acids. 2010 Aug; 39(3):713-26. PMID: 20165918.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    16. Chen P, Liu C, Burge L, Mahmood M, Southerland W, Gloster C. Prediction of inter-residue contact clusters from hydrophobic cores. Int J Data Min Bioinform. 2010; 4(6):722-34. PMID: 21355503.
      Citations:    Fields:    Translation:Cells
    17. Fang YY, Morris VR, Lingani GM, Long EC, Southerland WM. Genome-Targeted Drug Design: Understanding the Netropsin-DNA Interaction. Open Conf Proc J. 2010; 1:157-163. PMID: 21297883.
      Citations:    
    18. Hu ZJ, Bai L, Tizabi Y, Southerland W. Computational modeling study of human nicotinic acetylcholine receptor for developing new drugs in the treatment of alcoholism. Interdiscip Sci. 2009 Dec; 1(4):254-62. PMID: 20640803.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    19. Chen P, Liu C, Burge L, Mahmood M, Southerland W, Gloster C. Protein fold classification with genetic algorithms and feature selection. J Bioinform Comput Biol. 2009 Oct; 7(5):773-88. PMID: 19785045.
      Citations: 1     Fields:    Translation:Cells
    20. Chen P, Liu C, Burge L, Mahmood M, Southerland W, Gloster C. Prediction of inter-residue contact clusters from hydrophobic cores. Int J Data Min Bioinform. 2008 Dec 11; 2008:703-708. PMID: 20802820.
      Citations: 1     Fields:    
    21. Jackson PL, Scott KR, Southerland WM, Fang YY. Enaminones 8: CoMFA and CoMSIA studies on some anticonvulsant enaminones. Bioorg Med Chem. 2009 Jan 01; 17(1):133-40. PMID: 19059784.
      Citations: 5     Fields:    Translation:Humans
    22. Fleming ES, Perkins J, Easa D, Conde JG, Baker RS, Southerland WM, Dottin R, Benabe JE, Ofili EO, Bond VC, McClure SA, Sayre MH, Beanan MJ, Norris KC. The role of translational research in addressing health disparities: a conceptual framework. Ethn Dis. 2008; 18(2 Suppl 2):S2-155-60. PMID: 18646340.
      Citations: 23     Fields:    Translation:Humans
    23. Fleming ES, Perkins J, Easa D, Conde JG, Baker RS, Southerland WM, Dottin R, Benabe JE, Ofili EO, Bond VC, McClure SA, Sayre MH, Beanan MJ, Norris KC. Addressing health disparities through multi-institutional, multidisciplinary collaboratories. Ethn Dis. 2008; 18(2 Suppl 2):S2-161-7. PMID: 18646341.
      Citations: 12     Fields:    Translation:Humans
    24. Hu Z, Southerland W. WinDock: structure-based drug discovery on Windows-based PCs. J Comput Chem. 2007 Nov 15; 28(14):2347-51. PMID: 17476686.
      Citations: 6     Fields:    
    25. Das JR, Fryar-Tita EB, Zhou Y, Green S, Southerland WM, Bowen D. Sequence-dependent administration of 5-fluorouracil maintains methotrexate antineoplastic activity in human estrogen-negative breast cancer and protects against methotrexate cytotoxicity in human bone marrow. Anticancer Res. 2007 Nov-Dec; 27(6B):3791-9. PMID: 18225534.
      Citations:    Fields:    Translation:HumansCells
    26. Hu Z, Bowen D, Southerland WM, del Sol A, Pan Y, Nussinov R, Ma B. Ligand binding and circular permutation modify residue interaction network in DHFR. PLoS Comput Biol. 2007 Jun; 3(6):e117. PMID: 17571919.
      Citations: 22     Fields:    Translation:Cells
    27. Fryar-Tita EB, Das JR, Davis JH, Desoto JA, Green S, Southerland WM, Bowen D. Raloxifene and selective cell cycle specific agents: a case for the inclusion of raloxifene in current breast cancer treatment therapies. Anticancer Res. 2007 May-Jun; 27(3B):1393-9. PMID: 17595753.
      Citations: 3     Fields:    Translation:HumansCells
    28. Das JR, Fryar-Tita EB, Green S, Southerland WM, Bowen D. Sequence-dependent administration of raloxifene and 5-fluorouracil/pemetrexed protects against pemetrexed cytotoxicity in human bone marrow. Anticancer Res. 2007 Mar-Apr; 27(2):825-33. PMID: 17465208.
      Citations: 1     Fields:    Translation:HumansCells
    29. Nekhai S, Jerebtsova M, Jackson A, Southerland W. Regulation of HIV-1 transcription by protein phosphatase 1. Curr HIV Res. 2007 Jan; 5(1):3-9. PMID: 17266553.
      Citations: 24     Fields:    Translation:Cells
    30. Ammosova T, Berro R, Jerebtsova M, Jackson A, Charles S, Klase Z, Southerland W, Gordeuk VR, Kashanchi F, Nekhai S. Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription. Retrovirology. 2006 Nov 03; 3:78. PMID: 17083724.
      Citations: 54     Fields:    Translation:HumansCells
    31. Das JR, Fryar EB, Green S, Southerland WM, Bowen D. The protection against trimetrexate cytotoxicity in human bone marrow by sequence-dependent administration of raloxifene, 5-fluorouracil/trimetrexate. Anticancer Res. 2006 Nov-Dec; 26(6B):4279-86. PMID: 17201145.
      Citations:    Fields:    Translation:HumansCells
    32. Das JR, Fryar EB, Epie NN, Southerland WM, Bowen D. Raloxifene attenuation of methotrexate cytotoxicity in human bone marrow by sequence-dependent administration of raloxifene, 5-FU/methotrexate. Anticancer Res. 2006 May-Jun; 26(3A):1877-83. PMID: 16827120.
      Citations:    Fields:    Translation:Humans
    33. Fryar EB, Das JR, Davis JH, Desoto JA, Laniyan I, Southerland WM, Bowen D. Raloxifene attenuation of 5-FU/methotrexate cytotoxicity in human breast cancer cells: the importance of sequence in combination chemotherapy. Anticancer Res. 2006 May-Jun; 26(3A):1861-7. PMID: 16827118.
      Citations:    Fields:    Translation:HumansCells
    34. Yin J, Bowen D, Southerland WM. Barnase thermal titration via molecular dynamics simulations: detection of early denaturation sites. J Mol Graph Model. 2006 Jan; 24(4):233-43. PMID: 16213760.
      Citations: 4     Fields:    Translation:Cells
    35. Ammosova T, Jerebtsova M, Beullens M, Lesage B, Jackson A, Kashanchi F, Southerland W, Gordeuk VR, Bollen M, Nekhai S. Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein. J Biol Chem. 2005 Oct 28; 280(43):36364-71. PMID: 16131488.
      Citations: 36     Fields:    Translation:HumansCells
    36. De Soto JA, Bowen D, Davis JH, Southerland WM, Hawkins M. Sequence- and time-dependent antagonism between raloxifene and methotrexate in human breast cancer cells. Anticancer Res. 2002 Mar-Apr; 22(2A):1007-9. PMID: 12014617.
      Citations:    Fields:    Translation:HumansCells
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